you eat affects your mouth not only by building healthier teeth and
gums, but also by helping prevent tooth decay and gum disease. Learn how
to eat the best diet for your teeth, including the foods to eat,
beverages to drink, and what to avoid.
Recommended Fluoride Level in Drinking Water Changed
American Dental Association information on Fluoride
CDC Information on Water Fluoridation
January 1, 2011
HAPPY NEW YEAR TO ALL!____________________________
December 25, 2010
We wish all our friends and families a Happy and Safe Holiday Season.
We will see you in January.
Dr. Michelle Weddle started her term as Secretary of Central Dental Society component of the New Jersey Dental Association.
May 26, 2010
Autophagy, or "self-eating," is an essential component of cellular survival and defense against invading organisms. It is how the cell degrades and recycles material into amino acids that can be reused. Several neurological disorders, including Parkinson's and Alzheimer's disease, are associated with the buildup of polypeptides within neurons.
Current evidence suggests that if the affected cells could break down these plaque buildups, it would greatly increase the chances of recovery. The ability to activate autophagy within these cells could prove invaluable in treating neurodegenerative disorders.
"Although we do not yet completely understand how these diseases develop, we do know that the proteins clump together and form a plaque buildup in affected patients' neurons," said Ann Progulske-Fox, Ph.D., a researcher on the study, in a press release. "If we can direct the cell's own ability to break down waste products against the plaques, we could keep them from forming and potentially intercept the development of these and other diseases."
In previous studies, Progulske-Fox and her colleagues demonstrated that the bacterium Porphyromonas gingivalis had the ability to activate autophagy when exposed to a human cell line, suggesting the bacterium secreted some unknown substance that initiated the process.
In the current study, the researchers report on a mutant strain of P. gingivalis (PG0717) that does not induce autophagy.
"Understanding how P. gingivalis turns on autophagy in host cells could lead to novel therapeutics for the treatment of neurodegenerative disorders, as well as advancements in the general understanding of the autophagic pathway," Progulske-Fox said. "Study of the mutant will facilitate this understanding and the development of new potential strategies for the treatment of multiple diseases."
Copyright © 2010 DrBicuspid.com
Dentistry is a profession filled with people wanting to give back and take care of people in need. On July 17 and 18, New Jersey's finest dentists will be volunteering their time, care, skill, knowledge and judgement to those who need it most.
If you know of anyone who needs dental care but can not afford it, please pass along the information to them. To get the details, please click on the Pankey Dental Access Days link above.
April 2009 - Dr. Weddle invited to join the Vanguard Study Club.
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